Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730692 | 1.00 | TLR8 (0.51) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL10738786 | 0.94 | ALDH1A1 (0.53) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL10728812 | 0.85 | ALDH1A1 (0.39) | TLR8POLBALDH1A1KMT2ACNR1 | |
| SCHEMBL9006000 | 0.78 | TLR8 (0.57) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL10740315 | 0.75 | BRD4 (0.36) | POLBALDH1A1KMT2AGAA | |
| SCHEMBL28837797 | 0.74 | TLR8 (0.57) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25240227 | 0.72 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25267373 | 0.72 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL5287541 | 0.72 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25270261 | 0.72 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698348-A | 1H-imidazo[4,5-c]quinolines and their use as bronchodilating agents | RIKER LABORATORIES, INC. (US) | 1987-10-06 | — | — | US | disclosed |