Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 12/20 | 0.61 |
| ▸ | HRH1 | P35367 | 12/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737014 | 0.92 | KDM4E (0.62) | KDM4EALDH1A1TSHRGAA | |
| SCHEMBL10551353 | 0.82 | SIGMAR1 (0.71) | ALDH1A1TSHR | |
| SCHEMBL10970911 | 0.82 | HRH2 (0.58) | HRH2HRH1KDM4EALDH1A1TSHR | |
| SCHEMBL10576764 | 0.81 | SIGMAR1 (0.62) | ALDH1A1TSHR | |
| SCHEMBL11643622 | 0.81 | SLC6A4 (0.60) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11642419 | 0.80 | SLC6A4 (0.59) | ALDH1A1TSHR | |
| SCHEMBL10970913 | 0.80 | HRH2 (0.58) | HRH2HRH1KDM4EALDH1A1TSHR | |
| SCHEMBL10730870 | 0.80 | ALDH1A1 (0.73) | KDM4EALDH1A1TSHRGAA | |
| SCHEMBL9819950 | 0.80 | ALDH1A1 (0.62) | KDM4EALDH1A1TSHRGAA | |
| SCHEMBL10357706 | 0.79 | SIGMAR1 (0.77) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673684-A | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO CORPORATION (JP) | 1987-06-16 | — | — | US | disclosed |
| EP-0157420-A2 | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |