Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730870 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL27320487 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EPOLB | |
| SCHEMBL10737014 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL10730867 | 0.80 | HRH2 (0.61) | ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL13687245 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1KDM4E | |
| SCHEMBL10640352 | 0.78 | ALDH1A1 (0.95) | ALDH1A1KDM4ETSHRGAAMAPT | |
| SCHEMBL13995623 | 0.78 | HRH2 (0.51) | ALDH1A1KDM4ETSHRMAPTPOLB | |
| SCHEMBL13995270 | 0.76 | MEN1 (0.56) | ALDH1A1TSHRPOLB | |
| SCHEMBL28578060 | 0.76 | MEN1 (0.56) | ALDH1A1KDM4EPOLB | |
| SCHEMBL13150327 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |