Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725957 | 0.87 | PDGFRB (0.45) | PDGFRBPDGFRAALDH1A1MAPTNPC1 | |
| SCHEMBL10567603 | 0.83 | KDM4E (0.42) | ALDH1A1MAPTNPC1TDP1KMT2A | |
| SCHEMBL10725227 | 0.79 | MAPK1 (0.48) | PDGFRBPDGFRAALDH1A1MAPTNPC1 | |
| SCHEMBL10725223 | 0.79 | MAPK1 (0.48) | PDGFRBPDGFRAALDH1A1MAPTNPC1 | |
| SCHEMBL10364534 | 0.77 | S100B (0.36) | ALDH1A1MAPTHTTLMNA | |
| SCHEMBL10567037 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL10562633 | 0.73 | L3MBTL1 (0.40) | ALDH1A1HTTSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL10568135 | 0.69 | CYP19A1 (0.40) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL7562427 | 0.69 | ALDH1A1 (0.61) | PDGFRBPDGFRAALDH1A1MAPTNPC1 | |
| SCHEMBL12312144 | 0.69 | PDGFRB (0.57) | PDGFRBPDGFRAALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649142-A | 3,4-dihydro-1,3-disubstituted-6-(substituted phenylimino)-2(1H)-pyrimidinone useful as cardiotonic agent and anti-allergic agent | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0166564-A2 | Pyrimidone derivatives, preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |