Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981099 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL18142142 | 0.70 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL7132801 | 0.64 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL18261198 | 0.62 | CYP1A2 (0.33) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL27814772 | 0.62 | ALDH1A1 (0.46) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL16411257 | 0.62 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL31437683 | 0.59 | EEF2K (0.42) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL27651348 | 0.59 | MAPT (0.37) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL13903365 | 0.57 | ALOX15 (0.42) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL19675543 | 0.57 | ALDH1A1 (0.35) | KDM4EALDH1A1CYP1A2MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047568-B | Molded article and propylene resin composition | 三井化学株式会社 | 2020-06-09 | — | — | CN | disclosed |
| EP-2275457-B1 | Propylene-based polymer composition, and molded products, sheets, films, laminates and non-woven fabrics obtained therefrom | MITSUI CHEMICALS INC (JP) | 2016-11-23 | — | — | EP | disclosed |
| EP-2275451-B1 | Method for producing propylene-based copolymer | MITSUI CHEMICALS INC (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-1860149-B1 | PROPYLENE POLYMER COMPOSITION, USE THEREOF, AND PROCESS FOR PRODUCTION OF THERMOPLASTIC POLYMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 2016-06-15 | — | — | EP | disclosed |
| EP-2275457-A2 | Propylene polymer, propylene-based polymer composition, and use of these | Mitsui Chemicals, Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| EP-1803742-B1 | PROCESS FOR PRODUCING PROPYLENE POLYMER | MITSUI CHEMICALS INC (JP) | 2010-06-23 | — | — | EP | disclosed |
| EP-1900758-A1 | CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE | Mitsui Chemicals, Inc. (JP) | 2008-03-19 | — | — | EP | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |