Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 7/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10737425 | 0.99 | CCKBR (0.53) | CCKBROPRK1OPRD1OPRM1 | |
| SCHEMBL11144787 | 0.90 | OPRK1 (0.56) | CCKBROPRK1OPRD1OPRM1 | |
| SCHEMBL11138033 | 0.89 | CCKBR (0.69) | CCKBROPRK1OPRD1OPRM1 | |
| SCHEMBL10732104 | 0.87 | OPRK1 (0.54) | CCKBROPRK1OPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL10730349 | 0.86 | OPRK1 (0.53) | CCKBROPRK1OPRD1OPRM1 | |
| SCHEMBL11137502 | 0.85 | CCKBR (0.47) | CCKBROPRK1OPRD1OPRM1 | |
| SCHEMBL11144159 | 0.80 | OPRK1 (0.63) | CCKBROPRK1OPRD1OPRM1 | |
| SCHEMBL10730756 | 0.80 | CCKBR (0.41) | CCKBROPRK1OPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL11145247 | 0.79 | OPRK1 (0.62) | CCKBROPRK1OPRD1OPRM1 | |
| SCHEMBL11139219 | 0.78 | MTNR1A (0.46) | CCKBROPRK1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649137-A | ANALGESICS | KALI-CHEMIE PHARMA GMBH (DE) | 1987-03-10 | — | — | US | disclosed |
| EP-0068240-B1 | 2-ACYLAMINOMETHYL-1,4-BENZODIAZEPINE DERIVATIVES, THEIR PREPARATION AND INTERMEDIATES, AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | Kali-Chemie Pharma GmbH (DE) | 1985-09-25 | — | — | EP | disclosed |
| US-4497740-A | ANALGESICS | KALI-CHEMIE PHARMA GMBH (DE) | 1985-02-05 | — | — | US | disclosed |
| EP-0068240-A1 | 2-Acylaminomethyl-1,4-benzodiazepine derivatives, their preparation and intermediates, and pharmaceutical preparations containing them | Kali-Chemie Pharma GmbH (DE) | 1983-01-05 | — | — | EP | disclosed |