Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732024 | 1.00 | MAPT (0.52) | MAPTALDH1A1NPC1RECQLHSD11B1 | |
| SCHEMBL10731670 | 0.94 | MAPT (0.43) | MAPTALDH1A1NPC1RECQLLMNA | |
| SCHEMBL10719220 | 0.92 | ALDH1A1 (0.45) | MAPTALDH1A1NPC1HSD11B1LMNA | |
| SCHEMBL10731857 | 0.87 | MAPT (0.43) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL10731862 | 0.87 | MAPT (0.43) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL10727279 | 0.87 | ALDH1A1 (0.46) | MAPTALDH1A1NPC1HSD11B1LMNA | |
| SCHEMBL10727275 | 0.87 | ALDH1A1 (0.46) | MAPTALDH1A1NPC1HSD11B1LMNA | |
| SCHEMBL10727301 | 0.85 | KMT2A (0.47) | ALDH1A1HSD11B1LMNASMN1; SMN2HTT | |
| SCHEMBL10727300 | 0.85 | KMT2A (0.47) | ALDH1A1HSD11B1LMNASMN1; SMN2HTT | |
| SCHEMBL10716597 | 0.84 | ALDH1A1 (0.41) | MAPTALDH1A1NPC1HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |