Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732024 | 0.94 | MAPT (0.52) | MAPTGAAALDH1A1NPC1LMNA | |
| SCHEMBL10732032 | 0.94 | MAPT (0.52) | MAPTGAAALDH1A1NPC1LMNA | |
| SCHEMBL10716590 | 0.85 | MEN1 (0.44) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL10719220 | 0.84 | ALDH1A1 (0.45) | MAPTKMT2AGAAALDH1A1NPC1 | |
| SCHEMBL10731492 | 0.83 | PKM (0.47) | GAAALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL10719185 | 0.81 | CA1 (0.44) | GAAALDH1A1RAB9ACA1CA2 | |
| SCHEMBL10731862 | 0.81 | MAPT (0.43) | MAPTKMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL10731857 | 0.81 | MAPT (0.43) | MAPTKMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL10727275 | 0.80 | ALDH1A1 (0.46) | MAPTKMT2AGAAALDH1A1NPC1 | |
| SCHEMBL10727279 | 0.80 | ALDH1A1 (0.46) | MAPTKMT2AGAAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |