Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMP16 | P51512 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727301 | 1.00 | KMT2A (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL10731492 | 0.94 | PKM (0.47) | ALDH1A1RAB9AHSD11B1MMP2MMP8 | |
| SCHEMBL10719220 | 0.89 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL10732518 | 0.88 | HSD11B1 (0.46) | HSD11B1KEAP1 | |
| SCHEMBL10732521 | 0.88 | HSD11B1 (0.46) | HSD11B1KEAP1 | |
| SCHEMBL10732024 | 0.85 | MAPT (0.52) | ALDH1A1SMN1; SMN2HSD11B1HTTPOLB | |
| SCHEMBL10732032 | 0.85 | MAPT (0.52) | ALDH1A1SMN1; SMN2HSD11B1HTTPOLB | |
| SCHEMBL10727275 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL10727279 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL10730534 | 0.82 | HTR6 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |