Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.45 |
| ▸ | CTSD | P07339 | 5/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729075 | 0.89 | SIRT2 (0.43) | FKBP5CRBNSIRT2SIRT1SIRT3 | |
| SCHEMBL7717336 | 0.85 | CYP1A2 (0.42) | SIRT2SIRT1SIRT3CTSDALDH1A1 | |
| SCHEMBL6439316 | 0.84 | ALDH1A1 (0.44) | CRBNALDH1A1L3MBTL1TP53KDM4E | |
| SCHEMBL1423906 | 0.83 | ALDH1A1 (0.41) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| Caprolactam SCHEMBL3636353 | 0.81 | SIRT2 (0.54) | FKBP5CRBNSIRT2SIRT1SIRT3 | |
| SCHEMBL10380869 | 0.80 | ALDH1A1 (0.45) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL3503763 | 0.80 | ALDH1A1 (0.50) | CRBNALDH1A1L3MBTL1KDM4EPOLB | |
| Caprolactam SCHEMBL6668448 | 0.79 | CRBN (0.67) | FKBP5CRBNSIRT2SIRT1SIRT3 | |
| SCHEMBL9800093 | 0.79 | ALDH1A1 (0.46) | SIRT2SIRT1SIRT3ALDH1A1L3MBTL1 | |
| SCHEMBL9646435 | 0.78 | ALDH1A1 (0.53) | CRBNALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4638026-A | LACTAM ANTIOZONANT | VULNAX INTERNATIONAL LIMITED (FR) | 1987-01-20 | — | — | US | disclosed |