Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717336 | 0.98 | CYP1A2 (0.42) | ALDH1A1L3MBTL1NOS1NOS2CYP1A2 | |
| SCHEMBL9800093 | 0.95 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NOS1NOS2CYP1A2 | |
| SCHEMBL450579 | 0.93 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1NOS1NOS2CYP1A2 | |
| SCHEMBL18527023 | 0.93 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1NOS1NOS2CYP1A2 | |
| SCHEMBL10380869 | 0.93 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL3499721 | 0.89 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP1A2TP53MEN1 | |
| SCHEMBL6444135 | 0.89 | NOS1 (0.37) | ALDH1A1L3MBTL1NOS1NOS2KMT2A | |
| SCHEMBL6439316 | 0.87 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CYP1A2TP53KDM4E | |
| SCHEMBL5963378 | 0.83 | AR (0.35) | ALDH1A1L3MBTL1NOS1NOS2TP53 | |
| SCHEMBL10732167 | 0.83 | FKBP5 (0.46) | ALDH1A1L3MBTL1TP53KDM4ESIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175491-A1 | TOPICAL COMPOSITIONS OF APREMILAST | TORRENT PHARMACEUTICALS LIMITED (IN) | 2019-06-13 | — | — | US | claimed |
| EP-3471698-A1 | TOPICAL COMPOSITIONS OF APREMILAST | Torrent Pharmaceuticals Limited (IN) | 2019-04-24 | — | — | EP | claimed |
| WO-2017216738-A1 | TOPICAL COMPOSITIONS OF APREMILAST | TORRENT PHARMACEUTICALS LIMITED (IN) | 2017-12-21 | — | — | WO | claimed |
| EP-1922380-B1 | ACRYLIC PRESSURE SENSITIVE ADHESIVE COMPOSITION | LG CHEMICAL LTD (KR) | 2011-03-23 | — | — | EP | claimed |
| EP-1922380-A4 | ACRYLIC PRESSURE SENSITIVE ADHESIVE COMPOSITION | LG CHEMICAL LTD (KR) | 2009-08-05 | — | — | EP | claimed |
| EP-1922380-A1 | ACRYLIC PRESSURE SENSITIVE ADHESIVE COMPOSITION | LG Chem, Ltd. (KR) | 2008-05-21 | — | — | EP | claimed |
| US-20070191517-A1 | Acrylic pressure sensitive adhesive composition | LG CHEM, LTD. (KR) | 2007-08-16 | — | — | US | claimed |
| WO-2007021152-A1 | ACRYLIC PRESSURE SENSITIVE ADHESIVE COMPOSITION | LG CHEM, LTD. (KR) | 2007-02-22 | — | — | WO | claimed |
| CN-120157874-A | High-elasticity light nylon elastomer and hydrolytic polymerization preparation method thereof | 浙江恒逸石化研究院有限公司 | 2025-06-17 | — | — | CN | disclosed |
| US-11911463-B2 | Topical hyper-allergenic composition and method of treating using the same | ALLEAMIT INC. | 2024-02-27 | — | — | US | disclosed |
| US-20210015912-A1 | TOPICAL HYPER-ALLERGENIC COMPOSITION AND METHOD OF TREATING USING THE SAME | ALLEAMIT INC. | 2021-01-21 | — | — | US | disclosed |
| US-20190175491-A1 | TOPICAL COMPOSITIONS OF APREMILAST | TORRENT PHARMACEUTICALS LIMITED (IN) | 2019-06-13 | — | — | US | disclosed |
| EP-3471698-A1 | TOPICAL COMPOSITIONS OF APREMILAST | Torrent Pharmaceuticals Limited (IN) | 2019-04-24 | — | — | EP | disclosed |
| EP-3337474-A1 | QUANTITATIVE PERI-ORBITAL APPLICATION OF OPHTHALMOLOGY DRUGS | Jenivision Inc. (US) | 2018-06-27 | — | — | EP | disclosed |
| EP-0724570-B1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0897912-A1 | Amidino derivatives useful as nitric oxide synthase inhibitors | G.D. SEARLE & CO. (US) | 1999-02-24 | — | — | EP | disclosed |
| US-5854234-A | Amidino dervatives useful as nitric oxide synthase inhibitors | G. D. SEARLE & CO. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0724570-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011231-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G. D. SEARLE & CO. (US) | 1995-04-27 | — | — | WO | disclosed |
| US-4444829-A | Polyamide release film for sheet molding compound | ALLIED CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175491-A1 | TOPICAL COMPOSITIONS OF APREMILAST | TSLP, APRT, TPSB2 | ALDH1A1 61/4885L3MBTL1 4864/4885NOS1 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.