Sugi Predict

Sugi Predict / Compounds / SCHEMBL10732229

SCHEMBL10732229

SCHEMBL10732229

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 18/20 0.62
▸ CTSD P07339 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10752754 0.99 REN (0.62) RENCTSD
SCHEMBL10734041 0.96 REN (0.59) RENCTSD
SCHEMBL9716785 0.95 REN (0.69) RENCTSD
SCHEMBL9716796 0.93 REN (0.65) RENCTSD
SCHEMBL11110012 0.91 REN (0.68) RENCTSD
SCHEMBL10777493 0.89 REN (0.77) RENCTSD
SCHEMBL10600978 0.88 REN (0.63) RENCTSD
SCHEMBL11025160 0.88 REN (0.66) RENCTSD
SCHEMBL10826434 0.88 CMA1 (0.58) REN
SCHEMBL10826474 0.88 CMA1 (0.58) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0243477-A1 RENIN INHIBITORS AND METHODS FOR USING SAME SCHERING CORPORATION (US) 1987-11-04 — — EP disclosed
WO-1987002581-A1 RENIN INHIBITORS AND METHODS FOR USING SAME SCHERING CORPORATION (US) 1987-05-07 — — WO disclosed
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