SCHEMBL11110012

CC(C)C[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.68

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	15/20	0.68

▸	CTSD	P07339	1/20	0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9716785	0.96	REN (0.69)	RENCTSD
SCHEMBL10777493	0.94	REN (0.77)	RENCTSD
SCHEMBL9716796	0.93	REN (0.65)	RENCTSD
SCHEMBL10732229	0.91	REN (0.62)	RENCTSD
SCHEMBL10752754	0.91	REN (0.62)	RENCTSD
SCHEMBL11020013	0.90	REN (0.72)	RENCTSD
SCHEMBL10734041	0.89	REN (0.59)	RENCTSD
SCHEMBL11025160	0.88	REN (0.66)	RENCTSD
SCHEMBL10600978	0.86	REN (0.63)	RENCTSD
SCHEMBL10777425	0.86	REN (0.64)	RENCTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0111266-A2	Substituted tetrapeptides	CIBA-GEIGY AG (CH)	1984-06-20	—	—	EP	claimed
EP-0111266-A2	Substituted tetrapeptides	CIBA-GEIGY AG (CH)	1984-06-20	—	—	EP	disclosed