Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726989 | 0.81 | NPSR1 (0.64) | KMT2ANPSR1GAARAB9AALDH1A1 | |
| SCHEMBL10732207 | 0.81 | NPSR1 (0.37) | KMT2ASMN1; SMN2NPSR1GAARAB9A | |
| SCHEMBL10729009 | 0.79 | KDM4E (0.49) | KMT2ASMN1; SMN2GAARAB9AALDH1A1 | |
| SCHEMBL10732212 | 0.75 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2NPSR1CYP2C19RAB9A | |
| SCHEMBL9722714 | 0.69 | RAB9A (0.64) | KMT2ASMN1; SMN2GAARAB9AALDH1A1 | |
| SCHEMBL5109846 | 0.68 | KMT2A (0.65) | KMT2ASMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL10732640 | 0.68 | KMT2A (0.50) | KMT2ARAB9AALDH1A1NPC1HPGD | |
| SCHEMBL5638709 | 0.67 | KMT2A (0.70) | KMT2ASMN1; SMN2GAANPC1POLB | |
| SCHEMBL7172967 | 0.66 | KMT2A (0.74) | KMT2AGAARAB9AALDH1A1NPC1 | |
| SCHEMBL3731079 | 0.66 | GAA (0.56) | KMT2AGAARAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4672065-A | TOMATO LATE BLIGHT | CHEVRON RESEARCH COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4535087-A | FOR TOMATO LATE BLIGHT | CHEVRON RESEARCH COMPANY (US) | 1985-08-13 | — | — | US | disclosed |