Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.52 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410458 | 0.82 | KMT2A (0.61) | KMT2ALMNAPTPN7PTPN12PTPN22 | |
| SCHEMBL7433745 | 0.81 | LMNA (0.59) | KMT2ALMNAKDM4EPTGS2POLB | |
| SCHEMBL22307856 | 0.81 | KMT2A (0.69) | KMT2APTPN7PTPN12PTPN22POLB | |
| SCHEMBL8816518 | 0.81 | LMNA (0.58) | KMT2ALMNAKDM4EPTGS2ALDH1A1 | |
| SCHEMBL7172967 | 0.80 | KMT2A (0.74) | KMT2APTPN7PTPN12PTPN22POLB | |
| SCHEMBL5000478 | 0.80 | LMNA (0.62) | KMT2ALMNAKDM4EPOLBMAPT | |
| SCHEMBL10428803 | 0.79 | KMT2A (0.57) | KMT2ALMNAPOLBALDH1A1GAA | |
| SCHEMBL6815943 | 0.79 | LMNA (0.56) | KMT2ALMNAKDM4EPTGS2ALDH1A1 | |
| SCHEMBL9505425 | 0.79 | KMT2A (0.71) | KMT2APTPN7PTPN12PTPN22POLB | |
| SCHEMBL3729436 | 0.79 | KMT2A (1.00) | KMT2ALMNAPTPN7PTPN12PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645540-A | Preparation method of chlorophenoxycarboxylate | 山东润博生物科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| WO-2019179291-A2 | PREPARATION METHOD FOR CHLOROPHENOXYCARBOXYLATE | 山东润博生物科技有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179288-A2 | PREPARATION METHOD FOR CHLOROPHENOXYCARBOXYLATE | 山东润博生物科技有限公司 | 2019-09-26 | — | — | WO | disclosed |
| CN-108947820-A | Preparation method of chlorinated phenoxy carboxylic ester | 山东润博生物科技有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108947806-A | A kind of preparation method of chlorobenzene oxycarboxylic acid amine salt | 山东润博生物科技有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108947807-A | A kind of preparation method of chlorobenzene oxycarboxylic acid amine salt | 山东润博生物科技有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108947840-A | A kind of preparation method of chlorobenzene oxycarboxylic acid ester | 山东润博生物科技有限公司 | 2018-12-07 | — | — | CN | disclosed |
| US-7449581-B2 | 6-Substituted pyrido-pyrimidines | POCHE PALO ALTO LLC (US) | 2008-11-11 | — | — | US | disclosed |
| CN-100376571-C | 6-substituted pyrido-pyrimidines | HOFFMANN LA ROCHE (CH) | 2008-03-26 | — | — | CN | disclosed |
| US-20070135458-A1 | 6-Substituted pyrido-pyrimidines | CHEN JIAN J | 2007-06-14 | — | — | US | disclosed |
| US-7169794-B2 | 6-substituted pyrido-pyrimidines | ROCHE PALO ALTO LLC (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1361880-B1 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | EP | disclosed |
| US-20040116698-A1 | 6-Substituted pyrido-pyrimidines | CHEN JIAN JEFFREY (US) | 2004-06-17 | — | — | US | disclosed |
| CN-1503672-A | 6-substituted pyridopyrimidines | - | 2004-06-09 | — | — | CN | disclosed |
| US-6696566-B2 | SELECTIVE P38 KINASE INHIBITORS RELATIVE TO CYCLIN-DEPENDENT KINASES AND TYROSINE KINASES | SYNTEX (U.S.A.) LLC | 2004-02-24 | — | — | US | disclosed |
| EP-1361880-A2 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-20030171584-A1 | Treating p38 mediated disorders such as arthritis, Crohns disease, irritable bowel syndrome adult respiratory distress syndrome or chronic obstructive pulmonary disease. | SYNTEX (U.S.A.) LLC | 2003-09-11 | — | — | US | disclosed |
| WO-2002064594-A2 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135458-A1 | 6-Substituted pyrido-pyrimidines | P2RX6, P2RX1, P2RX7 | KMT2A 2116/4885LMNA 2628/4885PTPN7 2351/4885 |
| US-20030171584-A1 | Treating p38 mediated disorders such as arthritis, Crohns disease, irritable bowel syndrome adult respiratory distress syndrome or chronic obstructive pulmonary disease. | ARRB1, MAPK1, MAPK8 | KMT2A 3077/4885LMNA 4583/4885PTPN7 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.