Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29077372 | 0.86 | BACE1 (0.61) | BACE1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4347785 | 0.82 | BACE1 (0.58) | BACE1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6240232 | 0.82 | MEN1 (0.52) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL29768297 | 0.82 | BACE1 (0.58) | BACE1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31296110 | 0.82 | MEN1 (0.52) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL10733080 | 0.80 | ESR2 (0.50) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL10733095 | 0.80 | ESR2 (0.50) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3044443 | 0.77 | ESR2 (0.54) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL28184246 | 0.77 | BACE1 (0.60) | BACE1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7913572 | 0.76 | MAPT (0.65) | BACE1ESR1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452792-A | Acridine substituted phosphorus compounds and their insecticidal use | VELSICOL CHEMICAL CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |