Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737356 | 0.87 | MAPT (0.41) | RAB9AMAPK1NPC1MAPTNFKB1 | |
| SCHEMBL10739797 | 0.85 | CYP2D6 (0.47) | RAB9AMAPK1NPC1MAPTNFKB1 | |
| SCHEMBL10738457 | 0.85 | KMT2A (0.48) | RAB9AMAPK1NPC1MAPTNFKB1 | |
| SCHEMBL10737468 | 0.85 | MAPT (0.45) | RAB9AMAPK1NPC1MAPTNFKB1 | |
| SCHEMBL10736825 | 0.84 | MAPT (0.41) | RAB9AMAPK1NPC1MAPTNFKB1 | |
| SCHEMBL10732219 | 0.81 | ALDH1A1 (0.47) | RAB9AMAPK1NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8081306 | 0.80 | MAPT (0.50) | RAB9AMAPK1NPC1MAPTNFKB1 | |
| SCHEMBL30554021 | 0.79 | KCNJ1 (0.51) | RAB9AMAPTGAAMEN1KMT2A | |
| SCHEMBL1593910 | 0.78 | SMN1; SMN2 (0.55) | RAB9AMAPK1NPC1MAPTALDH1A1 | |
| SCHEMBL10961137 | 0.77 | SLC5A1 (0.44) | RAB9AMAPK1NPC1MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4686219-A | 11-(Piperazin- or homopiperazin-1-yl)-5H-imidazo-(2,1-C)(1,4)benzodiazepines useful as anti-allergics | BOEHRINGER INGELHEIM KG (DE) | 1987-08-11 | — | — | US | disclosed |