Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732659 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL10741876 | 0.86 | CREBBP (0.38) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL2743830 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL9667484 | 0.72 | TDP2 (0.48) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL10746773 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL6693673 | 0.68 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL10733388 | 0.68 | MEN1 (0.43) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL7236050 | 0.67 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL11789560 | 0.66 | CYP1A2 (0.45) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL11797014 | 0.65 | HTT (0.48) | ALDH1A1MAPTTSHRKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4686224-A | Oxindole antiinflammatory agents | PFIZER INC. (US) | 1987-08-11 | — | — | US | disclosed |
| US-4644005-A | ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1987-02-17 | — | — | US | disclosed |