Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.49 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744234 | 0.86 | PDE7A (0.49) | PDE7APDE7BALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL10741952 | 0.83 | PDE7A (0.44) | PDE7APDE7BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10736059 | 0.81 | PDE7A (0.50) | PDE7APDE7BNPSR1MAPTHTT | |
| SCHEMBL10738200 | 0.80 | PDE7A (0.51) | PDE7APDE7BNPSR1MAPTHTT | |
| SCHEMBL10734076 | 0.76 | KDR (0.56) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10741723 | 0.72 | CYP3A4 (0.50) | NPSR1TSHRSMN1; SMN2 | |
| SCHEMBL10741199 | 0.71 | USP2 (0.57) | MAPTHTTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9972171 | 0.70 | LMNA (0.74) | PDE7APDE7BNPSR1MAPTALDH1A1 | |
| SCHEMBL5030398 | 0.70 | MAPT (0.67) | PDE7APDE7BNPSR1MAPTALDH1A1 | |
| SCHEMBL19487245 | 0.69 | LMNA (0.77) | PDE7APDE7BALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |