Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741199 | 0.86 | USP2 (0.57) | SMN1; SMN2USP2L3MBTL1TDP1KDM4E | |
| SCHEMBL10744234 | 0.84 | PDE7A (0.49) | SMN1; SMN2 | |
| SCHEMBL10741313 | 0.83 | NPSR1 (0.55) | CYP3A4SMN1; SMN2NPSR1EGFRL3MBTL1 | |
| SCHEMBL10736269 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1EGFRL3MBTL1TDP1 | |
| SCHEMBL10733448 | 0.76 | SMN1; SMN2 (0.47) | CYP3A4SMN1; SMN2NPSR1EGFRL3MBTL1 | |
| SCHEMBL10739941 | 0.75 | PLA2G1B (0.47) | CYP3A4SMN1; SMN2NPSR1L3MBTL1KDM4E | |
| SCHEMBL1464587 | 0.74 | EGFR (0.67) | CYP3A4SMN1; SMN2EGFRL3MBTL1KDM4E | |
| SCHEMBL10740253 | 0.72 | TUBB4A (0.52) | TDP1POLBNPC1RAB9AKMT2A | |
| SCHEMBL10733928 | 0.72 | PDE7A (0.49) | SMN1; SMN2NPSR1TSHR | |
| SCHEMBL8845824 | 0.71 | KMT2A (0.57) | CYP3A4EGFRPOLBRXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |