Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.44 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744234 | 0.83 | PDE7A (0.49) | PDE7APDE7BALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL10733928 | 0.83 | PDE7A (0.49) | PDE7APDE7BALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL10737796 | 0.81 | PDE7A (0.47) | PDE7APDE7BMAT2ACTSDLMNA | |
| SCHEMBL10742041 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10734076 | 0.73 | KDR (0.56) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10827393 | 0.72 | LMNA (0.49) | MAT2ACTSDLMNAALDH1A1KCNH2 | |
| SCHEMBL10737297 | 0.71 | CTSD (0.44) | PDE7AMAT2ACTSDLMNAALDH1A1 | |
| SCHEMBL22720081 | 0.69 | MAT2A (0.43) | MAT2ACTSDLMNAALDH1A1KCNH2 | |
| SCHEMBL10741723 | 0.68 | CYP3A4 (0.50) | SMN1; SMN2TSHR | |
| SCHEMBL10741199 | 0.67 | USP2 (0.57) | LMNAALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |