Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10742303 | 0.85 | HPGD (0.32) | HPGDHTTHSD17B10MEN1LMNA | |
| SCHEMBL11163319 | 0.82 | MAPT (0.36) | HPGDHTTHSD17B10MEN1LMNA | |
| SCHEMBL11160179 | 0.80 | LMNA (0.35) | HPGDHTTHSD17B10MEN1LMNA | |
| SCHEMBL11166835 | 0.79 | CYP1A2 (0.30) | — | |
| SCHEMBL11187955 | 0.76 | ALDH1A1 (0.42) | HSD17B10KDM4EALDH1A1 | |
| SCHEMBL11159379 | 0.76 | HTR6 (0.38) | HPGDHTTHSD17B10 | |
| SCHEMBL11165428 | 0.75 | — | — | |
| SCHEMBL11163030 | 0.75 | POLB (0.40) | LMNA | |
| SCHEMBL11167932 | 0.75 | TP53 (0.40) | — | |
| SCHEMBL11153180 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705791-A | ANTICARCINOGENIC AGENTS, IMMUNOLOGY, SKIN DISORDERS | NYEGAARD & CO. A/S (NO) | 1987-11-10 | — | — | US | disclosed |
| US-4596870-A | Substituted pyrimidin-2-ones and the salts thereof | NYEGAARD & CO. A.S. (NO) | 1986-06-24 | — | — | US | disclosed |
| EP-0056319-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYEGAARD & CO. A/S (NO) | 1986-04-16 | — | — | EP | disclosed |
| EP-0056319-A2 | Substituted pyrimidin-2-ones and the salts thereof | NYEGAARD & CO. A/S (NO) | 1982-07-21 | — | — | EP | disclosed |