Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14675490 | 0.90 | MAPT (0.65) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL8357492 | 0.88 | MAPT (0.62) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL9389944 | 0.87 | MAPT (0.67) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL14675442 | 0.87 | MAPT (0.67) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL1129400 | 0.84 | MAPT (0.58) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL9439898 | 0.84 | MAPT (0.63) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL8361491 | 0.81 | MAPT (0.66) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL10475190 | 0.81 | ALDH1A1 (0.67) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL6689290 | 0.81 | PDK1 (0.69) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL6902202 | 0.81 | MAPT (0.66) | MAPTLMNAL3MBTL1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634701-A | Furan derivatives having anti-ulcer activity | AUSONIA FARMACEUTICI S.R.L. (IT) | 1987-01-06 | — | — | US | disclosed |