Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25024364 | 0.87 | LOXL2 (0.50) | LOXL2ALDH1A1CYP4F2CYP4A11MAPT | |
| SCHEMBL1574716 | 0.85 | CYP4F2 (0.52) | ALDH1A1CYP3A4CYP4F2CYP4A11MAPT | |
| SCHEMBL1574197 | 0.85 | LOXL2 (0.51) | LOXL2ALDH1A1CYP4F2CYP4A11MAPT | |
| SCHEMBL11801026 | 0.84 | L3MBTL1 (0.48) | LOXL2ALDH1A1CYP4F2CYP4A11MAPT | |
| SCHEMBL7384531 | 0.84 | ALDH1A1 (0.58) | LOXL2ALDH1A1CYP4F2CYP4A11MAPT | |
| SCHEMBL26144269 | 0.83 | LOXL2 (0.49) | LOXL2ALDH1A1CYP4F2CYP4A11MAPT | |
| SCHEMBL7384565 | 0.83 | LOXL2 (0.49) | LOXL2ALDH1A1CYP4F2CYP4A11MAPT | |
| SCHEMBL3509155 | 0.82 | KDM4E (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL2742811 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL21377435 | 0.81 | PTPN1 (0.64) | LOXL2ALDH1A1CYP4F2CYP4A11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | disclosed |
| US-4153413-A | DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |