Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 8/20 | 0.47 |
| ▸ | EGFR | P00533 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10987288 | 0.82 | EPHX2 (0.42) | EGFREPHX2L3MBTL1LMNAKMT2A | |
| SCHEMBL11286463 | 0.82 | L3MBTL1 (0.52) | CSF1REPHX2L3MBTL1LMNAKMT2A | |
| SCHEMBL11191736 | 0.82 | L3MBTL1 (0.41) | EGFREPHX2L3MBTL1LMNAKMT2A | |
| SCHEMBL10684964 | 0.80 | LMNA (0.45) | EPHX2L3MBTL1LMNAKMT2ATP53 | |
| SCHEMBL11225749 | 0.78 | MAPT (0.48) | EPHX2L3MBTL1LMNAKMT2ATP53 | |
| SCHEMBL11090798 | 0.78 | KMT2A (0.42) | EPHX2L3MBTL1LMNAKMT2ATP53 | |
| SCHEMBL10961514 | 0.78 | EPHX2 (0.43) | EPHX2L3MBTL1LMNAKMT2ATP53 | |
| SCHEMBL11097303 | 0.77 | EPHX2 (0.42) | EPHX2L3MBTL1LMNAKMT2ATP53 | |
| SCHEMBL10730420 | 0.77 | L3MBTL1 (0.42) | EPHX2L3MBTL1LMNAKMT2ATP53 | |
| SCHEMBL10734394 | 0.77 | KMT2A (0.42) | EPHX2L3MBTL1LMNAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675047-A | MONOCOTYLEDON WEES | ICI AUSTRALIA LIMITED, 1 NICHOLSON ST., MELBOURNE, VICTORIA, 3000, AUSTRALIA, A CORP. OF AUSTRALIA | 1987-06-23 | — | — | US | disclosed |
| EP-0044163-A2 | Quinazolinyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-01-20 | — | — | EP | disclosed |