Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985707 | 0.90 | CYP1A2 (0.38) | EPHX2L3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10985791 | 0.89 | LMNA (0.46) | EPHX2KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL11191736 | 0.85 | L3MBTL1 (0.41) | EPHX2KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL10975713 | 0.83 | KMT2A (0.43) | EPHX2KMT2AL3MBTL1LMNAPSEN1 | |
| SCHEMBL10734394 | 0.82 | KMT2A (0.42) | EPHX2KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL10737597 | 0.82 | CSF1R (0.47) | EPHX2KMT2AL3MBTL1LMNACYP1A2 | |
| SCHEMBL10977426 | 0.82 | LMNA (0.45) | EPHX2KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL10980423 | 0.78 | KMT2A (0.42) | EPHX2KMT2AL3MBTL1LMNAPSEN1 | |
| SCHEMBL10980006 | 0.78 | EPHX2 (0.42) | EPHX2KMT2AL3MBTL1LMNAPSEN1 | |
| SCHEMBL10684964 | 0.78 | LMNA (0.45) | EPHX2KMT2AL3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048539-B1 | ISOQUINOLYLOXY(AMINO)PHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR SYNTHESIS, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1985-08-28 | — | — | EP | disclosed |
| US-4409017-A | Herbicidal isoquinolinoxy- or isoquinolinamino-phenoxy alkane carboxylic acid derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-10-11 | — | — | US | disclosed |
| EP-0048539-A1 | Isoquinolyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-03-31 | — | — | EP | disclosed |