Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734345 | 0.86 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10736131 | 0.82 | ADRA2A (0.31) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10732292 | 0.79 | KDM4E (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10821055 | 0.65 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10821075 | 0.63 | KDM1A (0.33) | — | |
| SCHEMBL10821508 | 0.63 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10821118 | 0.63 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9751410 | 0.62 | KDM4E (0.39) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10730119 | 0.60 | ADRA2A (0.31) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL22006001 | 0.59 | DPP4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659719-A | CALCIUM OR SEROTONIN ANTAGONIST | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1987-04-21 | — | — | US | disclosed |