Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.76 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | CNR1 | P21554 | 1/20 | 0.76 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.76 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.76 |
| ▸ | THPO | P40225 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921251 | 0.90 | ADRB2 (0.73) | ADRB2ADRB1LMNATDP1ADRA1A | |
| SCHEMBL120842 | 0.88 | ADRB2 (0.71) | ADRB2ADRB1LMNATDP1ADRA1A | |
| SCHEMBL10961494 | 0.88 | ADRB2 (0.78) | ADRB2ADRB1LMNATDP1ADRA1A | |
| SCHEMBL6674480 | 0.88 | ADRB2 (0.78) | ADRB2ADRB1LMNATDP1ADRA1A | |
| SCHEMBL10072155 | 0.88 | ADRB2 (0.78) | ADRB2ADRB1LMNATDP1ADRA1A | |
| SCHEMBL9628892 | 0.88 | ADRB2 (0.78) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL4362 | 0.86 | ADRB2 (1.00) | ADRB2ADRB1LMNATDP1ADRA1A | |
| SCHEMBL6016784 | 0.86 | ADRB2 (0.77) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL18120 | 0.86 | ADRB2 (1.00) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Hydrochloric Acid SCHEMBL6016823 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1LMNATDP1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652672-A | BETA BLOCKERS | LINDNER WOLFGANG F (AT) | 1987-03-24 | — | — | US | disclosed |