Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10742628 | 0.90 | F2 (0.38) | ALDH1A1MAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL10745802 | 0.88 | DAO (0.35) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10737830 | 0.86 | KMT2A (0.41) | ALDH1A1MAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL10737230 | 0.85 | IDO1 (0.44) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10742281 | 0.79 | GRIN2B (0.37) | ALDH1A1MAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL10738569 | 0.74 | KMT2A (0.51) | ALDH1A1MAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL10735453 | 0.74 | HPGD (0.32) | ALDH1A1HSD17B10KMT2AKDM4EHPGD | |
| SCHEMBL10737268 | 0.73 | RAB9A (0.42) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10735574 | 0.73 | POLB (0.52) | ALDH1A1MAPTHSD17B10RAB9AKMT2A | |
| SCHEMBL10742303 | 0.72 | HPGD (0.32) | HSD17B10KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705791-A | ANTICARCINOGENIC AGENTS, IMMUNOLOGY, SKIN DISORDERS | NYEGAARD & CO. A/S (NO) | 1987-11-10 | — | — | US | disclosed |
| US-4596870-A | Substituted pyrimidin-2-ones and the salts thereof | NYEGAARD & CO. A.S. (NO) | 1986-06-24 | — | — | US | disclosed |
| EP-0056319-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYEGAARD & CO. A/S (NO) | 1986-04-16 | — | — | EP | disclosed |
| EP-0056319-A2 | Substituted pyrimidin-2-ones and the salts thereof | NYEGAARD & CO. A/S (NO) | 1982-07-21 | — | — | EP | disclosed |