Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10738423 | 0.88 | ALDH1A1 (0.41) | RAB9ANPC1GAAALDH1A1MAPT | |
| SCHEMBL10742628 | 0.84 | F2 (0.38) | DAORAB9ANPC1GAAALDH1A1 | |
| SCHEMBL10737230 | 0.80 | IDO1 (0.44) | RAB9ANPC1GAAALDH1A1MAPT | |
| SCHEMBL10811918 | 0.77 | EGLN1 (0.39) | RAB9ANPC1TYRHSD17B10NOTUM | |
| SCHEMBL10742281 | 0.75 | GRIN2B (0.37) | RAB9ANPC1GAAALDH1A1MAPT | |
| SCHEMBL11160179 | 0.71 | LMNA (0.35) | ALDH1A1HSD17B10KMT2AMEN1LMNA | |
| SCHEMBL10811880 | 0.70 | ALDH1A1 (0.49) | DAORAB9ANPC1GAAALDH1A1 | |
| SCHEMBL10735453 | 0.69 | HPGD (0.32) | ALDH1A1HSD17B10KMT2AMEN1LMNA | |
| SCHEMBL10735574 | 0.69 | POLB (0.52) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL11170879 | 0.68 | HPGD (0.47) | GAAALDH1A1HSD17B10LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705791-A | ANTICARCINOGENIC AGENTS, IMMUNOLOGY, SKIN DISORDERS | NYEGAARD & CO. A/S (NO) | 1987-11-10 | — | — | US | disclosed |
| US-4596870-A | Substituted pyrimidin-2-ones and the salts thereof | NYEGAARD & CO. A.S. (NO) | 1986-06-24 | — | — | US | disclosed |
| EP-0056319-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYEGAARD & CO. A/S (NO) | 1986-04-16 | — | — | EP | disclosed |
| EP-0056319-A2 | Substituted pyrimidin-2-ones and the salts thereof | NYEGAARD & CO. A/S (NO) | 1982-07-21 | — | — | EP | disclosed |