Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.52 |
| ▸ | ALPI | P09923 | 2/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082558 | 0.88 | L3MBTL1 (0.47) | ALPLALPICA2TDP1L3MBTL1 | |
| SCHEMBL10740092 | 0.84 | ALPL (0.47) | ALPLALPIENPP1CA2TDP1 | |
| SCHEMBL11844829 | 0.83 | CA12 (0.56) | CA2TDP1L3MBTL1GAAMAPK1 | |
| SCHEMBL11848703 | 0.83 | CA1 (0.56) | ALPLCA2TDP1L3MBTL1GAA | |
| SCHEMBL11852879 | 0.80 | MEN1 (0.56) | CA2TDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL11844234 | 0.80 | TDP1 (0.62) | ALPLALPICA2TDP1L3MBTL1 | |
| SCHEMBL8837781 | 0.77 | TDP1 (0.57) | ALPLALPIENPP1CA2TDP1 | |
| SCHEMBL11848172 | 0.77 | TDP1 (0.57) | ALPLALPIENPP1CA2TDP1 | |
| SCHEMBL11091725 | 0.77 | CA2 (0.46) | CA2TDP1L3MBTL1GAAMAPK1 | |
| SCHEMBL10652647 | 0.77 | CA12 (0.47) | ENPP1CA2TDP1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639463-A | Substituted phenylsulfonyloxybenzimidazolecarbamates and anthelmintic compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0115039-A1 | Substituted phenylsulfonyloxybenzimidazole carbamates, process for their preparation and their application as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |