Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739938 | 0.88 | TDP1 (0.57) | NPSR1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL10742041 | 0.85 | SMN1; SMN2 (0.44) | NPSR1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL10744270 | 0.84 | NPSR1 (0.53) | NPSR1SMN1; SMN2EGFRDPP4TDP1 | |
| SCHEMBL10737433 | 0.84 | TDP1 (0.64) | NPSR1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL10741723 | 0.83 | CYP3A4 (0.50) | NPSR1SMN1; SMN2EGFRTDP1CYP3A4 | |
| SCHEMBL10736269 | 0.82 | SMN1; SMN2 (0.55) | NPSR1SMN1; SMN2EGFRTDP1ALDH1A1 | |
| SCHEMBL10744234 | 0.78 | PDE7A (0.49) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10735119 | 0.74 | TDP1 (0.57) | NPSR1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL7635781 | 0.73 | SMN1; SMN2 (0.47) | NPSR1SMN1; SMN2EGFRDPP4ALDH1A1 | |
| SCHEMBL10733448 | 0.73 | SMN1; SMN2 (0.47) | NPSR1SMN1; SMN2EGFRCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |