Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489532 | 0.81 | ALOX5 (0.49) | ALDH1A1ALOX5DAOPOLBTDP1 | |
| SCHEMBL164188 | 0.80 | ALOX5 (0.44) | ALDH1A1ALOX5DAOPOLBTDP1 | |
| SCHEMBL10743661 | 0.79 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1GAAALOX5POLB | |
| SCHEMBL1520622 | 0.79 | ALOX5 (0.46) | ALDH1A1ALOX5DAOPOLBTDP1 | |
| SCHEMBL10747469 | 0.78 | ALOX5 (0.43) | ALDH1A1ALOX5DAOPOLBTDP1 | |
| SCHEMBL10745762 | 0.77 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1GAAALOX5POLB | |
| SCHEMBL341475 | 0.76 | GABBR2 (0.67) | GAAALOX5DAOKMT2AGABBR2 | |
| SCHEMBL21273058 | 0.75 | ALOX5 (0.40) | ALDH1A1ALOX5DAOPOLBTDP1 | |
| SCHEMBL21273024 | 0.75 | ALOX5 (0.40) | ALDH1A1ALOX5DAOPOLBTDP1 | |
| SCHEMBL10747456 | 0.75 | FFAR1 (0.49) | ALDH1A1L3MBTL1GAAALOX5DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1009553-B | PREPARATION METHOD OF COMPOUNDS OF 5,6-DIHYDRO-4H-CYOCLOPENTADIENE (B) THIOPHENE-6-CARBOXYLIC ACID | LYON INDUSTRAL MEDICINE CO (FR) | 1990-09-12 | — | — | CN | disclosed |
| US-4649153-A | ANTIINFLAMMATORY, ANALGESICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1987-03-10 | — | — | US | disclosed |
| CN-85106178-A | 5,6 dihydros-4H-cyclopenta (b) thiophene-6-carboxylic acid compound and contain the preparation method of the medicine of these compounds | — | 1987-03-04 | — | — | CN | disclosed |