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Sugi Predict / Compounds / Methoxymethane

Methoxymethane

Methoxymethane

SCHEMBL10740980

C=CC(=O)NCOC(=O)CO.COC

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ ZDHHC20 Q5W0Z9 1/20 0.38
▸ ZDHHC2 Q9UIJ5 1/20 0.38
▸ TGM2 P21980 3/20 0.32
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10740970 0.81 TSHR (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL7768846 0.81 TSHR (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL13275928 0.79 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28986894 0.78 ZDHHC20 (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL7776385 0.76 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL138455 0.76 — —
Methoxymethane SCHEMBL422310 0.76 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL16805860 0.76 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
Methoxymethane SCHEMBL27789567 0.75 GAA (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
Ethylene Glycol SCHEMBL9479208 0.75 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4689264-A COPOLYMER OF (METH)ACRYLIC ESTER, OPTIONALLY ETHERIFIED (METH) ACRYLAMIDEGLYCOLIC ACID ESTER ROHM GMBH CHEMISCHE FABRIK (DE) 1987-08-25 — — US disclosed