Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTPRG | P23470 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823732 | 0.90 | GFER (0.54) | FKBP1AGFERCYP1A2CYP3A4ALPG | |
| SCHEMBL10746094 | 0.87 | FKBP1A (0.53) | FKBP1AGFERCYP2C9L3MBTL1KCNQ3 | |
| SCHEMBL10741387 | 0.87 | L3MBTL1 (0.47) | GFERCYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL11821844 | 0.86 | FKBP1A (0.52) | FKBP1AGFERCYP2C9L3MBTL1KCNQ3 | |
| Ammonia Solution, Strong SCHEMBL11820558 | 0.86 | FKBP1A (0.52) | FKBP1AGFERCYP2C9L3MBTL1KCNQ3 | |
| SCHEMBL11819040 | 0.86 | FKBP1A (0.52) | FKBP1AGFERCYP2C9L3MBTL1KCNQ3 | |
| SCHEMBL11825095 | 0.86 | FKBP1A (0.52) | FKBP1AGFERCYP2C9L3MBTL1KCNQ3 | |
| SCHEMBL11821280 | 0.86 | FKBP1A (0.52) | FKBP1AGFERCYP2C9L3MBTL1KCNQ3 | |
| SCHEMBL11820125 | 0.86 | FKBP1A (0.52) | FKBP1AGFERCYP2C9L3MBTL1KCNQ3 | |
| SCHEMBL11819472 | 0.85 | FKBP1A (0.47) | FKBP1AGFERCYP1A2CYP3A4ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663344-A | ANTIPYRETICS, ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1987-05-05 | — | — | US | disclosed |