Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741661 | 0.92 | MAPT (0.53) | L3MBTL1CYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL10745596 | 0.88 | L3MBTL1 (0.49) | L3MBTL1TP53MAPTHPGDNPSR1 | |
| SCHEMBL10746093 | 0.88 | LRRK2 (0.48) | L3MBTL1CYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL10747092 | 0.87 | CFTR (0.48) | L3MBTL1CYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL10741558 | 0.87 | FKBP1A (0.47) | L3MBTL1CYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL10744540 | 0.84 | CFTR (0.47) | L3MBTL1CYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL10740889 | 0.81 | MAPT (0.49) | L3MBTL1CYP1A2CYP2C9CYP2C19TP53 | |
| SCHEMBL11823732 | 0.77 | GFER (0.54) | L3MBTL1CYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL11382713 | 0.76 | MAPT (0.49) | L3MBTL1CYP1A2CYP3A4ALPGCYP2C9 | |
| SCHEMBL24060649 | 0.75 | MAPT (0.41) | L3MBTL1CYP1A2CYP2C19TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663344-A | ANTIPYRETICS, ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1987-05-05 | — | — | US | disclosed |