Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979663 | 0.88 | LMNA (0.62) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL4006491 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL11100909 | 0.81 | HTT (0.72) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL10966260 | 0.81 | LMNA (0.62) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7043647 | 0.80 | LMNA (0.66) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL16966571 | 0.79 | KDM4E (0.65) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL3316012 | 0.79 | KDM4E (0.65) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL29938478 | 0.79 | LMNA (0.60) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL9331793 | 0.79 | L3MBTL1 (0.59) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL11286223 | 0.79 | LMNA (0.60) | LMNASMN1; SMN2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663347-A | ANTIINFLAMMATORY, ANTIALLERGENS, CARDIOVASCULAR | MERCK FROSST CANADA, INC. (CA) | 1987-05-05 | — | — | US | disclosed |