SCHEMBL1074262

SCHEMBL1074262

CC(C)c1[c]cc(-c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.39
ALDH1A1 P00352 2/20 0.39
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CYP1A2 P05177 2/20 0.36
GAA P10253 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
CYP2C19 P33261 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP3A4 P08684 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP3 P08254 1/20 0.36
BCL2L1 Q07817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457428 0.73 ALDH1A1 (0.43) ALDH1A1SLC6A4CYP1A2CYP2C9MAPK1
SCHEMBL841559 0.71 ALDH1A1 (0.41) PTGS2ALDH1A1SLC6A4CYP1A2GAA
SCHEMBL1370233 0.71 ALDH1A1 (0.36) PTGS2ALDH1A1SLC6A4
SCHEMBL2958548 0.70 ALDH1A1 (0.45) ALDH1A1CYP1A2GAAMAPK1CYP3A4
SCHEMBL1188027 0.70 TYR (0.34) ALDH1A1GAA
SCHEMBL221706 0.70 ACHE (0.33) SLC6A2CYP1A2TDP1
SCHEMBL2448169 0.70 ALDH1A1 (0.45) ALDH1A1CYP1A2GAAMAPK1CYP3A4
Biphenyl SCHEMBL27656690 0.69 ALDH1A1 (0.69) PTGS2ALDH1A1SLC6A4CYP1A2GAA
SCHEMBL20833031 0.69 PTGS2 (0.58) PTGS2ALDH1A1CYP1A2CYP3A4TAAR1
SCHEMBL40528 0.69 PTGS2 (0.58) PTGS2ALDH1A1CYP1A2CYP3A4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1184954-C Sun protection agents BIOTEC ASA (NO) 2005-01-19 CN claimed
CN-1347306-A Sunscreen formulations BIOTEC ASA (NO) 2002-05-01 CN claimed
EP-3389621-A1 EMULSIONS HAVING UV SUNSCREEN FACTORS AND CARNOSINES Symrise AG (DE) 2018-10-24 EP disclosed
EP-3389619-A1 PREPARATIONS COMPRISING CARNOSINES Symrise AG (DE) 2018-10-24 EP disclosed
CN-103664593-B There is the polyglycerin ester of special polyglycereol oligomer distribution 赢创德固赛有限公司 2017-03-01 CN disclosed
CN-102197022-B Alkyl sulfosuccinate mixtures and their use COGNIS IP MAN GMBH 2014-11-05 CN disclosed
CN-102007137-B Alkyl and/or alkenyl ether of aklyl and/or alkenyl(poly)glycosides and use thereof COGNIS IP MAN GMBH 2014-09-17 CN disclosed
CN-101677922-B Hydrocarbon mixture and use thereof COGNIS IP MAN GMBH 2014-03-26 CN disclosed
CN-102811703-A Sun protection compositions BAYER MATERIALSCIENCE AG 2012-12-05 CN disclosed
CN-101688155-B Phosphate-free dishwasher detergent with excellent rinsing power BASF SE 2012-01-11 CN disclosed
CN-102307623-A Dolichos biflorus extract for use in cosmetic skin treatment COGNIS IP MAN GMBH 2012-01-04 CN disclosed
CN-1347307-A Cosmetic preparation BIOTEC ASA (NO) 2002-05-01 CN disclosed
CN-1347302-A Cosmetic preparations BIOTEC ASA (NO) 2002-05-01 CN disclosed
CN-1347306-A Sunscreen formulations BIOTEC ASA (NO) 2002-05-01 CN disclosed
WO-2002024667-A1 4-AMINO-QUINAZOLINES MERCK PATENT GMBH (DE) 2002-03-28 WO disclosed
WO-2002024666-A2 4-AMINO-QUINAZOLINES MERCK PATENT GMBH (DE) 2002-03-28 WO disclosed
EP-1144381-A2 SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GmbH (DE) 2001-10-17 EP disclosed
EP-1133475-A1 SUBSTITUTED BENZO DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GmbH (DE) 2001-09-19 EP disclosed
WO-2000032577-A2 SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GMBH (DE) 2000-06-08 WO disclosed
WO-2000031039-A1 SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GMBH (DE) 2000-06-02 WO disclosed