Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741425 | 0.86 | HTR2A (0.46) | SLC18A2HTR2ASLC6A3POLBMAPT | |
| SCHEMBL10742646 | 0.74 | ALDH1A1 (0.48) | SLC18A2HTR2ASLC6A3POLBMAPT | |
| SCHEMBL7324114 | 0.74 | DRD2 (0.43) | HTR2ASLC6A3MAPT | |
| SCHEMBL10742660 | 0.70 | PDE9A (0.40) | PDE9ATLR9TLR8TLR7 | |
| SCHEMBL8556573 | 0.67 | SLC18A3 (0.44) | HTR2A | |
| SCHEMBL8524117 | 0.65 | PLD2 (0.36) | — | |
| SCHEMBL8809958 | 0.64 | SLC18A2 (0.44) | SLC18A2HTR2ASLC6A3MAPT | |
| SCHEMBL13246028 | 0.64 | CA12 (0.54) | POLBMAPTRXFP1CACNA1GFEN1 | |
| SCHEMBL3894977 | 0.63 | HTR2A (0.76) | SLC18A2HTR2ASLC6A3MAPTCACNA1G | |
| Hydrochloric Acid SCHEMBL10737791 | 0.62 | HTR2A (0.75) | SLC18A2HTR2ASLC6A3MAPTCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665075-A | ANTISEROTONINE AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-05-12 | — | — | US | claimed |