Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1073185 | 0.85 | KDM4E (0.32) | CYP1A2ALDH1A1CA2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18142142 | 0.84 | ALDH1A1 (0.34) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL18261198 | 0.79 | CYP1A2 (0.33) | CYP1A2CYP2C9CYP2C19ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL13505559 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL1072326 | 0.73 | BACE1 (0.31) | — | |
| SCHEMBL21500716 | 0.69 | CYP2C9 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL3674984 | 0.68 | — | — | |
| SCHEMBL27489165 | 0.67 | CYP2C9 (0.44) | CYP1A2CYP2C9CYP2C19ALDH1A1CA2 | |
| Water SCHEMBL28480832 | 0.67 | CYP2C9 (0.44) | CYP1A2CYP2C9CYP2C19ALDH1A1CA2 | |
| SCHEMBL21796360 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868116-B | Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof | 三井化学株式会社 | 2022-12-09 | — | — | CN | disclosed |
| CN-110312618-B | Laminated body | 三井化学株式会社 | 2021-09-07 | — | — | CN | disclosed |
| CN-110325360-B | Laminated body | 三井化学株式会社 | 2021-07-20 | — | — | CN | disclosed |
| CN-111868116-A | Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof | 三井化学株式会社 | 2020-10-30 | — | — | CN | disclosed |
| CN-108047568-B | Molded article and propylene resin composition | 三井化学株式会社 | 2020-06-09 | — | — | CN | disclosed |
| CN-107406646-B | Resin composition and use thereof | 三井化学株式会社 | 2020-06-09 | — | — | CN | disclosed |
| WO-2019180802-A1 | ETHYLENE/α-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, PRODUCTION METHOD THEREFOR, AND USE | 三井化学株式会社 | 2019-09-26 | — | — | WO | disclosed |
| EP-2275457-B1 | Propylene-based polymer composition, and molded products, sheets, films, laminates and non-woven fabrics obtained therefrom | MITSUI CHEMICALS INC (JP) | 2016-11-23 | — | — | EP | disclosed |
| EP-2275451-B1 | Method for producing propylene-based copolymer | MITSUI CHEMICALS INC (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-1860149-B1 | PROPYLENE POLYMER COMPOSITION, USE THEREOF, AND PROCESS FOR PRODUCTION OF THERMOPLASTIC POLYMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 2016-06-15 | — | — | EP | disclosed |
| EP-2275457-A2 | Propylene polymer, propylene-based polymer composition, and use of these | Mitsui Chemicals, Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-7795194-B2 | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| EP-1803742-B1 | PROCESS FOR PRODUCING PROPYLENE POLYMER | MITSUI CHEMICALS INC (JP) | 2010-06-23 | — | — | EP | disclosed |
| EP-1900758-A1 | CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE | Mitsui Chemicals, Inc. (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-20060116303-A1 | decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability | MITSUI CHEMICALS, INC. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |