SCHEMBL10744950

SCHEMBL10744950

c1ccc(Oc2cccc(CCCc3ccc[nH]3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 10/20 0.45
DAO P14920 1/20 0.43
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4350635 0.81 HRH3 (0.50) DAO
SCHEMBL7714735 0.77 HRH3 (0.55) DAO
SCHEMBL17104827 0.76 HRH3 (0.53) DAO
SCHEMBL9799721 0.75 MAOB (0.65) FDFT1
SCHEMBL5545164 0.74 FDFT1 (0.51) FDFT1DAOFFAR1
SCHEMBL10106347 0.74 MAOA (0.52) FDFT1
SCHEMBL7774935 0.74 CYP4F2 (0.56) FDFT1FFAR1
SCHEMBL9331970 0.74 FDFT1 (0.51) FDFT1DAOFFAR1
SCHEMBL6795855 0.74 LTA4H (0.55) FDFT1
SCHEMBL9799443 0.74 FDFT1 (0.51) FDFT1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4644009-A ANTIINFLAMMATORY AGENTS, ANTIALLERGENS USV PHARMACEUTICAL CORPORATION (US) 1987-02-17 US claimed
US-4644009-A ANTIINFLAMMATORY AGENTS, ANTIALLERGENS USV PHARMACEUTICAL CORPORATION (US) 1987-02-17 US disclosed