SCHEMBL7714735

SCHEMBL7714735

c1ccc(CCCCc2ccc[nH]2)cc1

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.55
MAOA P21397 1/20 0.48
DAO P14920 1/20 0.47
MAOB P27338 2/20 0.47
SIGMAR1 Q99720 1/20 0.45
GPR84 Q9NQS5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17104827 0.98 HRH3 (0.53) HRH3MAOADAOSIGMAR1GPR84
SCHEMBL4350635 0.96 HRH3 (0.50) HRH3MAOADAOSIGMAR1
SCHEMBL7475165 0.87 TAAR1 (0.52) MAOADAOMAOBGPR84
SCHEMBL7003873 0.87 GPR84 (0.41) HRH3MAOADAOGPR84
Pyridine SCHEMBL28242946 0.86 HRH3 (0.50) HRH3DAO
SCHEMBL8955030 0.84 GPR84 (0.44) HRH3MAOAGPR84
SCHEMBL28268734 0.78 GPR84 (0.53) GPR84
SCHEMBL10744950 0.77 FDFT1 (0.45) DAO
SCHEMBL16241398 0.77 CHKA (0.45) MAOASIGMAR1
SCHEMBL4687381 0.77 GPR84 (0.35) HRH3MAOAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111670180-A Fluoroalkenyl compounds, process for their preparation and their use PI工业有限公司 2020-09-15 CN disclosed
US-20160032413-A1 NANOPRODUCT COMPRISING LACTOBACILLUS REUTERI DAN080 USEFUL IN PROPHYLAXIS AND MEDICINE, BOTH HUMAN AND VETERINARY AND MEDICAL USE OF THE SAME KRUSZEWSKA DANUTA (PL) 2016-02-04 US disclosed
WO-2013180585-A1 NANOPRODUCT COMPRISING LACTOBACILLUS REUTERI DAN080 USEFUL IN PROPHYLAXIS AND MEDICINE, BOTH HUMAN AND VETERINARY AND MEDICAL USE OF THE SAME KRUSZEWSKA DANUTA (PL) 2013-12-05 WO disclosed
EP-2457576-A1 New Lactobacillus reuteri strain useful in medical and veterinary prohylaxis and treatment Eurochit Danuta Kruszewska (PL) 2012-05-30 EP disclosed
US-6436649-B1 COMPETITIVE BINDING WITH ANTI-HAPTEN ANTIBODY IN SOLUTION CONTAINING REPORTER MOLECULE SUBSTRATE; ADDING B-LACTAMASE QUANTITATIVE ANALYSIS USING VISIBLE OR ULTRAVIOLET RADIATION LE REGION WALLONE (BE) 2002-08-20 US disclosed