Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501642 | 0.84 | POLB (0.36) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL10747300 | 0.82 | NR4A2 (0.33) | ALDH1A1MEN1KMT2AHSD17B10METAP2 | |
| SCHEMBL10745465 | 0.82 | METAP2 (0.48) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL10747716 | 0.82 | MPI (0.35) | ALDH1A1METAP2 | |
| SCHEMBL10746681 | 0.81 | MAT2A (0.41) | — | |
| SCHEMBL10501694 | 0.80 | METAP2 (0.44) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL10747582 | 0.79 | METAP2 (0.40) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL10748075 | 0.78 | MAPT (0.40) | ALDH1A1MEN1KMT2AKDM4EMETAP2 | |
| SCHEMBL10501085 | 0.77 | MAPT (0.33) | ALDH1A1MEN1KMT2AKDM4EPKM | |
| SCHEMBL10749778 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |