Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502337 | 0.84 | ALDH1A1 (0.38) | MPIPHOSPHO1ALDH1A1METAP2SMN1; SMN2 | |
| SCHEMBL10747300 | 0.82 | NR4A2 (0.33) | ALDH1A1METAP2 | |
| SCHEMBL10747513 | 0.82 | MPI (0.50) | MPIPHOSPHO1ALDH1A1METAP2SMN1; SMN2 | |
| SCHEMBL10745189 | 0.82 | ALDH1A1 (0.34) | ALDH1A1METAP2 | |
| SCHEMBL10748075 | 0.81 | MAPT (0.40) | ALDH1A1METAP2RAB9ARXFP1 | |
| SCHEMBL10501250 | 0.80 | METAP2 (0.44) | MPIPHOSPHO1ALDH1A1METAP2SMN1; SMN2 | |
| SCHEMBL10747582 | 0.79 | METAP2 (0.40) | MPIPHOSPHO1ALDH1A1METAP2HPGD | |
| SCHEMBL10746681 | 0.78 | MAT2A (0.41) | — | |
| SCHEMBL10501096 | 0.77 | KDM4E (0.34) | MPIALDH1A1RAB9AL3MBTL1HPGD | |
| SCHEMBL10746448 | 0.72 | TXNRD1 (0.43) | ALDH1A1METAP2RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |