Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000724 | 0.82 | HTT (0.45) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL7499725 | 0.82 | HTT (0.45) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL29053272 | 0.80 | ALDH1A1 (0.38) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL27830130 | 0.79 | THRB (0.38) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL27478065 | 0.75 | ALDH1A1 (0.43) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL27852103 | 0.75 | ALDH1A1 (0.43) | HTTLMNAMAPTALDH1A1PKM | |
| Water SCHEMBL11456518 | 0.75 | HTT (0.40) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL20267254 | 0.73 | HTT (0.43) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL20267257 | 0.73 | HTT (0.43) | HTTLMNAMAPTALDH1A1PKM | |
| SCHEMBL29031298 | 0.72 | THRB (0.33) | HTTLMNAMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665066-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0186463-A2 | Beta-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |