Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20267257 | 1.00 | HTT (0.43) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL28000724 | 0.86 | HTT (0.45) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL7499725 | 0.86 | HTT (0.45) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL10348791 | 0.84 | HTT (0.38) | HTTMAPTLMNAPKMALDH1A1 | |
| Water SCHEMBL11456518 | 0.79 | HTT (0.40) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL29053272 | 0.78 | ALDH1A1 (0.38) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL27830130 | 0.76 | THRB (0.38) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL2041342 | 0.74 | PKM (0.42) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL28036689 | 0.74 | RAB9A (0.55) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL10745463 | 0.73 | HTT (0.35) | HTTMAPTLMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555095-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018108125-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-06-21 | — | — | WO | disclosed |