Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | PMM2 | O15305 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747704 | 0.86 | HTT (0.41) | ALDH1A1LMNAPKMNPC1RAB9A | |
| SCHEMBL10748416 | 0.85 | METAP2 (0.48) | ALDH1A1LMNAPKMKDM4EMAPT | |
| SCHEMBL10746643 | 0.81 | METAP2 (0.38) | ALDH1A1LMNAPKMNPC1RAB9A | |
| SCHEMBL10745614 | 0.78 | METAP2 (0.35) | ALDH1A1LMNAPKMKDM4EMAPT | |
| SCHEMBL10502231 | 0.74 | METAP2 (0.37) | ALDH1A1LMNAPKMKDM4EMAPT | |
| SCHEMBL10749736 | 0.72 | KDM4E (0.35) | ALDH1A1LMNAPKMKDM4EMAPT | |
| SCHEMBL10501392 | 0.71 | METAP2 (0.34) | ALDH1A1LMNAPKMKDM4EMAPT | |
| SCHEMBL10501619 | 0.71 | EP300 (0.45) | ALDH1A1LMNAPKMRAB9ASMN1; SMN2 | |
| SCHEMBL10744989 | 0.71 | KAT2A (0.47) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10764046 | 0.71 | METAP2 (0.48) | ALDH1A1LMNAPKMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |