Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 2/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | PMM2 | O15305 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYBB | P04839 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746484 | 0.84 | METAP2 (0.54) | METAP2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10745614 | 0.82 | METAP2 (0.35) | METAP2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10746138 | 0.81 | ALDH1A1 (0.35) | METAP2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10502231 | 0.81 | METAP2 (0.37) | METAP2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10747704 | 0.78 | HTT (0.41) | METAP2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10501619 | 0.78 | EP300 (0.45) | METAP2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10749736 | 0.76 | KDM4E (0.35) | METAP2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10746112 | 0.75 | NPC1 (0.43) | METAP2ALDH1A1KMT2AMAPTMPI | |
| SCHEMBL10744989 | 0.75 | KAT2A (0.47) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL10501392 | 0.75 | METAP2 (0.34) | METAP2KDM4EALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |