Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2A | Q92830 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746112 | 0.82 | NPC1 (0.43) | TP53NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5916972 | 0.82 | KAT2A (0.57) | KAT2AKAT2BTP53HSD17B10NPSR1 | |
| SCHEMBL10744992 | 0.81 | MAPT (0.52) | TP53NPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL10746279 | 0.80 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10745118 | 0.79 | RAB9A (0.53) | NPC1RAB9ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL10748167 | 0.77 | ALDH1A1 (0.51) | TP53HSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10746643 | 0.75 | METAP2 (0.38) | TP53HSD17B10NPC1RAB9ANPSR1 | |
| SCHEMBL10745614 | 0.75 | METAP2 (0.35) | TP53HSD17B10NPSR1MEN1KMT2A | |
| SCHEMBL10501392 | 0.73 | METAP2 (0.34) | TP53HSD17B10NPSR1MEN1KMT2A | |
| SCHEMBL10502231 | 0.73 | METAP2 (0.37) | TP53HSD17B10NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |