Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 12/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733513 | 0.93 | DRD4 (0.47) | DRD4DRD3DRD2AGERABCC8 | |
| SCHEMBL11075834 | 0.90 | DRD4 (0.46) | DRD4DRD3DRD2AGERABCC8 | |
| SCHEMBL10727725 | 0.89 | DRD4 (0.57) | DRD4DRD3DRD2 | |
| SCHEMBL10718308 | 0.89 | AGER (0.46) | DRD4DRD3DRD2AGERABCC8 | |
| SCHEMBL11152721 | 0.89 | DRD4 (0.49) | DRD4DRD3DRD2AGERABCC8 | |
| SCHEMBL10814244 | 0.86 | DRD4 (0.52) | DRD4DRD3DRD2ABCC8 | |
| SCHEMBL10817683 | 0.86 | DRD4 (0.51) | DRD4DRD3DRD2ABCC8 | |
| SCHEMBL10719910 | 0.86 | HTR4 (0.55) | DRD2 | |
| SCHEMBL10813139 | 0.85 | DRD4 (0.51) | DRD4DRD3DRD2ABCC8 | |
| SCHEMBL10721734 | 0.80 | DRD2 (0.60) | DRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013138-B1 | AZABICYCLOALKYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-12-07 | — | — | EP | claimed |
| EP-0220339-A1 | Azabicycloalkyl derivatives | BEECHAM GROUP PLC (GB) | 1987-05-06 | — | — | EP | disclosed |
| US-4599420-A | GASTROINTESTINAL DISORDERS, ANTIEMETIC, PSYCHOSIS | BEECHAM GROUP LTD. (GB) | 1986-07-08 | — | — | US | disclosed |
| US-4544660-A | DOPAMINE ANTAGONIST | BEECHAM GROUP P.L.C. (GB) | 1985-10-01 | — | — | US | disclosed |
| EP-0013138-B1 | AZABICYCLOALKYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-12-07 | — | — | EP | disclosed |
| EP-0081054-A2 | Azabicyclo alkyl derivatives | BEECHAM GROUP PLC (GB) | 1983-06-15 | — | — | EP | disclosed |
| US-4273778-A | TREATMENT OF GASTROINTESTINAL DISORDERS, NERVOUS SYSTEM DISORDERS, AND PSYCHOLOGICAL DISORDERS | BEECHAM GROUP, LIMITED (GB) | 1981-06-16 | — | — | US | disclosed |
| EP-0013138-A1 | Azabicycloalkyl derivatives, a process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-07-09 | — | — | EP | disclosed |